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1

Drug Discovery and Natural Products: End of an Era or an Endless Frontier?

Li, J. W.-H., Vederas, J. C.

Journal:

Year:

2009

Language:

english

File:

PDF, 340 KB

english, 2009

2

Equity research and valuation: Jet Airways

Ramanchi, Radhika, Mehta, Sunita, Vedera, Madhavi

Journal:

Emerging Markets Case Studies Collection

Year:

2017

Language:

english

File:

PDF, 212 KB

english, 2017

3

Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates

Cochrane, Stephen A., Vederas, John C.

Journal:

Medicinal Research Reviews

Year:

2014

Language:

english

File:

PDF, 912 KB

english, 2014

4

Soybean meal-induced enteritis in Atlantic salmon ( Salmo salar) and Chinook salmon ( Oncorhynchus tshawytscha ) but not in pink salmon ( O . gorbuscha )

Booman, Marije, Forster, Ian, Vederas, John C., Groman, David B., Jones, Simon R.M.

Journal:

Year:

2018

Language:

english

File:

PDF, 570 KB

english, 2018

5

Draft Genome Sequence of the Thermophilic Bacterium Bacillus licheniformis SMIA-2, an Antimicrobial- and Thermostable Enzyme-Producing Isolate from Brazilian Soil

Bernardo, Samara Pinto Custodio, Rosana, Albert Remus R., de Souza, Adriane Nunes, Chiorean, Sorina, Martins, Meire Lelis Leal, Vederas, John C., Gill, Steven R.

Journal:

Microbiology Resource Announcements

Year:

2020

File:

PDF, 173 KB

2020

6

Serine and Threonine β-Lactones: A New Class of Hepatitis A Virus 3C Cysteine Proteinase Inhibitors

Lall, Manjinder S., Ramtohul, Yeeman K., James, Michael N. G., Vederas, John C.

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 168 KB

english, 2002

7

Two-peptide bacteriocins produced by lactic acid bacteria

Sylvie Garneau, Nathaniel I Martin, John C Vederas

Journal:

Year:

2002

Language:

english

File:

PDF, 523 KB

english, 2002

8

Antimicrobial Leucocin Analogues with a Disulfide Bridge Replaced by a Carbocycle or by Noncovalent Interactions of Allyl Glycine Residues

Derksen, Darren J., Stymiest, Jake L., Vederas, John C.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 119 KB

english, 2006

9

Peptide Aldehyde Inhibitors of Hepatitis A Virus 3C Proteinase

Malcolm, Bruce A., Lowe, Christopher, Shechosky, Shirley, McKay, Ryan T., Yang, Chi Ching, Shah, Vibhakar J., Simon, Reyna J., Vederas, John C., Smith, Daniel V.

Journal:

Year:

1995

Language:

english

File:

PDF, 922 KB

english, 1995

10

Synthesis of Oxytocin Analogues with Replacement of Sulfur by Carbon Gives Potent Antagonists with Increased Stability

Stymiest, Jake L., Mitchell, Bryan F., Wong, Susan, Vederas, John C.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 608 KB

english, 2005

11

Synthesis of 3-fluorodiaminopimelic acid isomers as inhibitors of diaminopimelate epimerase: stereocontrolled enzymatic elimination of hydrogen fluoride

Gelb, Michael H., Lin, Yukang, Pickard, Michael A., Song, Yonghong, Vederas, John C.

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 1.52 MB

english, 1990

12

Stereochemistry of lysine formation by meso-diaminopimelate decarboxylase from wheat germ: use of proton-carbon-13 NMR shift correlation to detect stereospecific deuterium labeling

Kelland, Janice G., Palcic, Monica M., Pickard, Michael A., Vederas, John C.

Journal:

Year:

1985

Language:

english

File:

PDF, 608 KB

english, 1985

13

Structure of Subtilosin A, an Antimicrobial Peptide from Bacillus s ubtilis with Unusual Posttranslational Modifications Linking Cysteine Sulfurs to α-Carbons of Phenylalanine and Threonine

Kawulka, Karen, Sprules, Tara, McKay, Ryan T., Mercier, Pascal, Diaper, Christopher M., Zuber, Peter, Vederas, John C.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

14

Intact incorporation of acetate-derived di- and tetraketides during biosynthesis of dehydrocurvularin, a macrolide phytotoxin from Alternaria cinerariae

Yoshizawa, Yuko, Li, Zhe, Reese, Paul B., Vederas, John Christopher

Journal:

Journal of the American Chemical Society

Year:

1990

Language:

english

File:

PDF, 257 KB

english, 1990

15

Book Reviews: : Comprehensive Natural Products Chemistry. Volumes 1 to 8.

Simpson, Thomas J., R. Hanson, James, B. Herbert, Richard, Robins, David J., Vederas, John C., Schofield, Christopher J., Mann, John

Journal:

Natural Product Reports

Year:

1999

Language:

english

File:

PDF, 32 KB

english, 1999

16

Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent

Cochrane, Rachel V. K., Sanichar, Randy, Lambkin, Gareth R., Reiz, Béla, Xu, Wei, Tang, Yi, Vederas, John C.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 2.82 MB

english, 2016

17

Catalytic mechanism and properties of pyridoxal 5′-phosphate independent racemases: how enzymes alter mismatched acidity and basicity

Fischer, Conrad, Ahn, Yeong-Chan, Vederas, John C.

Journal:

Natural Product Reports

Year:

2019

Language:

english

File:

PDF, 2.79 MB

english, 2019

18

Solid-Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2

Vijaya R. Pattabiraman, Shaun M. K. McKinnie, John C. Vederas

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 513 KB

english, 2008

19

Titelbild: Solid-Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2 (Angew. Chem. 49/2008)

Vijaya R. Pattabiraman, Shaun M. K. McKinnie, John C. Vederas

Journal:

Angewandte Chemie

Year:

2008

Language:

german

File:

PDF, 1.02 MB

german, 2008

20

The 3D Solution Structure of Thurincin H, a Bacteriocin with Four Sulfur to α-Carbon Crosslinks

Clarissa S. Sit, Marco J. van Belkum, Ryan T. McKay, Prof. Randy W. Worobo, Prof. John C. Vederas

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

21

Solid-Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2

Vijaya R. Pattabiraman, Shaun M. K. McKinnie, John C. Vederas

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 514 KB

english, 2008

22

Cover Picture: Solid-Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2 (Angew. Chem. Int. Ed. 49/2008)

Vijaya R. Pattabiraman, Shaun M. K. McKinnie, John C. Vederas

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

23

The 3D Solution Structure of Thurincin H, a Bacteriocin with Four Sulfur to α-Carbon Crosslinks

Clarissa S. Sit, Marco J. van Belkum, Ryan T. McKay, Prof. Randy W. Worobo, Prof. John C. Vederas

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

24

Peptide amidation in an invertebrate: Purification, characterization, and inhibition of peptidylglycine α-hydroxylating monooxygenase from the heads of honeybees (apis mellifera)

T. Mark Zabriskie, Michael Klinge, Christine M. Szymanski, Hengmiao Cheng, John C. Vederas

Journal:

Archives of Insect Biochemistry and Physiology

Year:

1994

Language:

english

File:

PDF, 1.28 MB

english, 1994

25

Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes

Chantel D. Campbell, John C. Vederas

Journal:

Year:

2010

Language:

english

File:

PDF, 815 KB

english, 2010

26

Hydrophobic Interactions as Substitutes for a Conserved Disulfide Linkage in the Type IIa Bacteriocins, Leucocin A and Pediocin PA-1

Darren J. Derksen, Marc A. Boudreau, John C. Vederas

Journal:

Year:

2008

Language:

english

File:

PDF, 320 KB

english, 2008

27

Substitution of a Conserved Disulfide in the Type IIa Bacteriocin, Leucocin A, with L-Leucine and L-Serine Residues: Effects on Activity and Three-Dimensional Structure

Dr. Clarissa S. Sit, Christopher T. Lohans, Dr. Marco J. van Belkum, Chantel D. Campbell, Mark Miskolzie, Prof. John C. Vederas

Journal:

Year:

2012

Language:

english

File:

PDF, 626 KB

english, 2012

28

ChemInform Abstract: Synthesis of Protein Farnesyltransferase and Protein Geranylgeranyltransferase Inhibitors: Rapid Access to Chaetomellic Acid A and Its Analogues.

E. S. RATEMI, J. M. DOLENCE, C. D. POULTER, J. C. VEDERAS

Journal:

Year:

1997

File:

PDF, 31 KB

1997

29

ChemInform Abstract: Modification of the Swern Oxidation: Use of Stoichiometric Amounts of an Easily Separable, Recyclable, and Odorless Sulfoxide That Can Be Polymer-Bound.

Y. LIU, J. C. VEDERAS

Journal:

Year:

1997

File:

PDF, 28 KB

1997

30

ChemInform Abstract: Synthesis of a Chiral Azodicarboxamide Containing a Bridging Binaphthyl Moiety: Electrophilic Amination Reactions of Achiral Ester Enolates

J. M. HARRIS, R. MCDONALD, J. C. VEDERAS

Journal:

Year:

1997

File:

PDF, 30 KB

1997

31

ChemInform Abstract: Synthesis of Tripeptide Inhibitors of Peptidylglycine α- Amidating Monooxygenase (PAM) Containing D- and L-Styrylglycine.

M. D. ANDREWS, K. A. O'CALLAGHAN, J. C. VEDERAS

Journal:

Year:

1997

File:

PDF, 37 KB

1997

32

ChemInform Abstract: Stereoselective Synthesis of meso-2,6-Diaminopimelic Acid and Its Selectively Protected Derivatives.

Y. GAO, P. LANE-BELL, J. C. VEDERAS

Journal:

Year:

1998

File:

PDF, 36 KB

1998

33

ChemInform Abstract: Biosynthetic Incorporation of Advanced Precursors into Dehydrocurvularin, a Polyketide Phytotoxin from Alternaria cinerariae.

Yaoquan Liu, Zhe Li, John C. Vederas

Journal:

Year:

1999

File:

PDF, 30 KB

1999

34

ChemInform Abstract: Unsaturated α-Aminopimelic Acids as Potent Inhibitors of meso-Diaminopimelic Acid (DAP) D-Dehydrogenase.

Andrew Sutherland, Jennifer F. Caplan, John C. Vederas

Journal:

Year:

1999

File:

PDF, 36 KB

1999

35

ChemInform Abstract: The First Isolation of an Alkoxy-N,N-dialkylaminodifluorosulfane from the Reaction of an Alcohols and DAST: An Efficient Synthesis of (2S,3R,6S)-3-Fluoro-2,6-diaminopimelic Acid.

Andrew Sutherland, John C. Vederas

Journal:

Year:

1999

File:

PDF, 35 KB

1999

36

ChemInform Abstract: β-Lactones as a New Class of Cysteine Proteinase Inhibitors: Inhibition of Hepatitis A Virus 3C Proteinase by N-Cbz-serine β-Lactone.

Manjinder S. Lall, Constantine Karvellas, John C. Vederas

Journal:

Year:

1999

File:

PDF, 28 KB

1999

37

ChemInform Abstract: Azodicarboxamides: A New Class of Cysteine Proteinase Inhibitor for Hepatitis A Virus and Human Rhinovirus 3C Enzymes.

Richard D. Hill, John C. Vederas

Journal:

Year:

2000

File:

PDF, 28 KB

2000

38

ChemInform Abstract: Conversion of Cyclic Nonaketides to Lovastatin and Compactin by a lovC Deficient Mutant of Aspergillus terreus.

Karine Auclair, Jonathan Kennedy, C. Richard Hutchinson, John C. Vederas

Journal:

Year:

2001

File:

PDF, 24 KB

2001

39

ChemInform Abstract: The First Stereospecific Synthesis of L-Tetrahydrodipicolinic Acid; a Key Intermediate of Diaminopimelate Metabolism.

Jennifer F. Caplan, Andrew Sutherland, John C. Vederas

Journal:

Year:

2002

File:

PDF, 30 KB

2002

40

ChemInform Abstract: Pseudoxazolones, a New Class of Inhibitors for Cysteine Proteinases: Inhibition of Hepatitis A Virus and Human Rhinovirus 3C Proteinases.

Yeeman K. Ramtohul, Nathaniel I. Martin, Lara Silkin, Michael N. G. James, John C. Vederas

Journal:

Year:

2002

File:

PDF, 28 KB

2002

41

ChemInform Abstract: Conjugate Addition of Radicals Generated from Diacyloxyiodobenzenes to Dehydroamino Acid Derivatives; a Synthesis of Diaminopimelic Acid Analogues.

Andrew Sutherland, John C. Vederas

Journal:

Year:

2002

File:

PDF, 32 KB

2002

42

ChemInform Abstract: Serine and Threonine β-Lactones: A New Class of Hepatitis A Virus 3C Cysteine Proteinase Inhibitors.

Manjinder S. Lall, Yeeman K. Ramtohul, Michael N. G. James, John C. Vederas

Journal:

Year:

2002

File:

PDF, 31 KB

2002

43

Synthesis of Pseudoxazolones and Their Inhibition of the 3C Cysteine Proteinases from Hepatitis A Virus and Human Rhinovirus-14.

Yeeman K. Ramtohul, Nathaniel I. Martin, Lara Silkin, Michael N. G. James, John C. Vederas

Journal:

Year:

2002

File:

PDF, 33 KB

2002

44

Synthesis and Evaluation of Keto-Glutamine Analogues as Inhibitors of Hepatitis A Virus 3C Proteinase.

Yeeman K. Ramtohul, Michael N. G. James, John C. Vederas

Journal:

Year:

2002

File:

PDF, 28 KB

2002

45

Monacolin N, a Compound Resulting from Derailment of Type I Iterative Polyketide Synthase Function en route to Lovastatin.

John L. Sorensen, John C. Vederas

Journal:

Year:

2003

File:

PDF, 61 KB

2003

46

Synthesis of β-Cyclopropylalanines by Photolysis of Diacyl Peroxides.

Rajendra P. Jain, John C. Vederas

Journal:

Year:

2004

File:

PDF, 143 KB

2004

47

ChemInform Abstract: Fundamental Functionality: Recent Developments in Understanding the Structure—Activity Relationships of Lantibiotic Peptides

Avena C. Ross, John C. Vederas

Journal:

Year:

2011

File:

PDF, 18 KB

2011

48

Biosynthesis of the Cytochalasans. Part III. 13C-NMR. of cytochalasin B (phomin) and cytochalasin D. Incorporation of [1-13C]- and [2-13C]-sodium acetate

Werner Graf, Jean-Louis Robert, John C. Vederas, Christoph Tamm, Philippa H. Solomon, Iwao Miura, Koji Nakanishi

Journal:

Helvetica Chimica Acta

Year:

1974

Language:

english

File:

PDF, 683 KB

english, 1974

49

Biosynthesis of Cytochalasans. Part 4. The mode of incorporation of common naturally-occurring carboxylic acids into cytochalasin D

John C. Vederas, Werner Graf, Lucien David, Christoph Tamm

Journal:

Helvetica Chimica Acta

Year:

1975

Language:

english

File:

PDF, 1.52 MB

english, 1975

50

Biosynthesis of Cytochalasans. Part 6. The Mode of Incorporation of Phenylalanine into Cytochalasin D

John C. Vederas, Christoph Tamm

Journal:

Helvetica Chimica Acta

Year:

1976

Language:

english

File:

PDF, 598 KB

english, 1976